Diagnosis and management of chronic graft‐versus‐host disease
Identifieur interne : 001406 ( Main/Exploration ); précédent : 001405; suivant : 001407Diagnosis and management of chronic graft‐versus‐host disease
Auteurs : Fiona L. Dignan [Royaume-Uni] ; Persis Amrolia [Royaume-Uni] ; Andrew Clark [Royaume-Uni] ; Jacqueline Cornish [Royaume-Uni] ; Graham Jackson [Royaume-Uni] ; Prem Mahendra [Royaume-Uni] ; Julia J. Scarisbrick [Royaume-Uni] ; Peter C. Taylor [Royaume-Uni] ; Bronwen E. Shaw [Royaume-Uni] ; Michael N. Potter [Royaume-Uni]Source :
- British Journal of Haematology [ 0007-1048 ] ; 2012-07.
English descriptors
- Teeft :
- Acute disease, Acute gvhd, Alefacept, Alemtuzumab, Allogeneic, Allogeneic hematopoietic, American journal, Arora, Azathioprine, Bcsh, Blackwell publishing, Bone marrow transplantation, British committee, British journal, British society, Busca, Calcineurin, Calcineurin inhibitors, Cell transplantation, Cgvhd, Chronic, Chronic disease, Chronic graft, Chronic gvhd, Ciclosporin, Clinical features, Clinical practice, Clinical response, Clinical trials, Clofazimine, Complete response, Complete response rate, Complete responses, Consensus conference, Corticosteroid, Couriel, Current evidence, Cutaneous, Cyclophosphamide, Daclizumab, Deeg, Dignan, Evaluable, Evaluable patients, Extracorporeal, Extracorporeal photochemotherapy, Extracorporeal photopheresis, Filipovich, Further research, Giralt, Graft, Greinix, Group report, Guideline, Gvhd, Haematology, Health consensus development project, Hematology, Hematopoietic, High risk, Host disease, Hydroxychloroquine, Imatinib, Infectious complications, Inhibitor, Initial therapy, Initial treatment, Jacobsohn, Line treatment, Mammalian target, Marrow, Marrow transplantation, Methotrexate, Mofetil, Mtor, Mycophenolate, Mycophenolate mofetil, National institutes, Oncology, Option, Other agents, Other organs, Overall survival, Overlap syndrome, Paediatric patients, Partial response, Partial responses, Pavletic, Pentostatin, Photopheresis, Prednisolone, Primary endpoint, Primary treatment, Prospective study, Pulmonary gvhd, Randomized, Randomized studies, Randomized trial, Refractory, Refractory cgvhd, Refractory cutaneous, Refractory disease, Regimen, Response rate, Retrospective, Retrospective series, Retrospective study, Rituximab, Scarisbrick, Second line treatment, Second line treatment option, Separate document, Shulman, Side effects, Sirolimus, Socie, Steroid, Storb, Supportive care, Systemic treatment, Tacrolimus, Task force, Thalidomide, Third line option, Third line treatment options, Thrombotic microangiopathy, Toxicity, Transplant, Transplantation, Vogelsang, Weisdorf.
Abstract
A joint working group established by the Haemato‐oncology subgroup of the British Committee for Standards in Haematology (BCSH) and the British Society for Bone Marrow Transplantation (BSBMT) has reviewed the available literature and made recommendations for the diagnosis and management of chronic graft‐versus‐host disease (GvHD). This guideline includes recommendations for the diagnosis and staging of chronic GvHD as well as primary treatment and options for patients with steroid‐refractory disease. The goal of treatment should be the effective control of GvHD while minimizing the risk of toxicity and relapse.
Url:
DOI: 10.1111/j.1365-2141.2012.09128.x
Affiliations:
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type="ISSN">0007-1048</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Acute disease</term><term>Acute gvhd</term><term>Alefacept</term><term>Alemtuzumab</term><term>Allogeneic</term><term>Allogeneic hematopoietic</term><term>American journal</term><term>Arora</term><term>Azathioprine</term><term>Bcsh</term><term>Blackwell publishing</term><term>Bone marrow transplantation</term><term>British committee</term><term>British journal</term><term>British society</term><term>Busca</term><term>Calcineurin</term><term>Calcineurin inhibitors</term><term>Cell transplantation</term><term>Cgvhd</term><term>Chronic</term><term>Chronic disease</term><term>Chronic graft</term><term>Chronic gvhd</term><term>Ciclosporin</term><term>Clinical features</term><term>Clinical practice</term><term>Clinical response</term><term>Clinical trials</term><term>Clofazimine</term><term>Complete response</term><term>Complete response rate</term><term>Complete responses</term><term>Consensus conference</term><term>Corticosteroid</term><term>Couriel</term><term>Current evidence</term><term>Cutaneous</term><term>Cyclophosphamide</term><term>Daclizumab</term><term>Deeg</term><term>Dignan</term><term>Evaluable</term><term>Evaluable patients</term><term>Extracorporeal</term><term>Extracorporeal photochemotherapy</term><term>Extracorporeal photopheresis</term><term>Filipovich</term><term>Further research</term><term>Giralt</term><term>Graft</term><term>Greinix</term><term>Group report</term><term>Guideline</term><term>Gvhd</term><term>Haematology</term><term>Health consensus development project</term><term>Hematology</term><term>Hematopoietic</term><term>High risk</term><term>Host disease</term><term>Hydroxychloroquine</term><term>Imatinib</term><term>Infectious complications</term><term>Inhibitor</term><term>Initial therapy</term><term>Initial treatment</term><term>Jacobsohn</term><term>Line treatment</term><term>Mammalian target</term><term>Marrow</term><term>Marrow transplantation</term><term>Methotrexate</term><term>Mofetil</term><term>Mtor</term><term>Mycophenolate</term><term>Mycophenolate mofetil</term><term>National institutes</term><term>Oncology</term><term>Option</term><term>Other agents</term><term>Other organs</term><term>Overall survival</term><term>Overlap syndrome</term><term>Paediatric patients</term><term>Partial response</term><term>Partial responses</term><term>Pavletic</term><term>Pentostatin</term><term>Photopheresis</term><term>Prednisolone</term><term>Primary endpoint</term><term>Primary treatment</term><term>Prospective study</term><term>Pulmonary gvhd</term><term>Randomized</term><term>Randomized studies</term><term>Randomized trial</term><term>Refractory</term><term>Refractory cgvhd</term><term>Refractory cutaneous</term><term>Refractory disease</term><term>Regimen</term><term>Response rate</term><term>Retrospective</term><term>Retrospective series</term><term>Retrospective study</term><term>Rituximab</term><term>Scarisbrick</term><term>Second line treatment</term><term>Second line treatment option</term><term>Separate document</term><term>Shulman</term><term>Side effects</term><term>Sirolimus</term><term>Socie</term><term>Steroid</term><term>Storb</term><term>Supportive care</term><term>Systemic treatment</term><term>Tacrolimus</term><term>Task force</term><term>Thalidomide</term><term>Third line option</term><term>Third line treatment options</term><term>Thrombotic microangiopathy</term><term>Toxicity</term><term>Transplant</term><term>Transplantation</term><term>Vogelsang</term><term>Weisdorf</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A joint working group established by the Haemato‐oncology subgroup of the British Committee for Standards in Haematology (BCSH) and the British Society for Bone Marrow Transplantation (BSBMT) has reviewed the available literature and made recommendations for the diagnosis and management of chronic graft‐versus‐host disease (GvHD). This guideline includes recommendations for the diagnosis and staging of chronic GvHD as well as primary treatment and options for patients with steroid‐refractory disease. The goal of treatment should be the effective control of GvHD while minimizing the risk of toxicity and relapse.</div></front></TEI><affiliations><list><country><li>Royaume-Uni</li></country><region><li>Angleterre</li><li>Grand Londres</li><li>Midlands de l'Ouest</li></region><settlement><li>Birmingham</li><li>Londres</li></settlement></list><tree><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Dignan, Fiona L" sort="Dignan, Fiona L" uniqKey="Dignan F" first="Fiona L." last="Dignan">Fiona L. Dignan</name></region><name sortKey="Amrolia, Persis" sort="Amrolia, Persis" uniqKey="Amrolia P" first="Persis" last="Amrolia">Persis Amrolia</name><name sortKey="Clark, Andrew" sort="Clark, Andrew" uniqKey="Clark A" first="Andrew" last="Clark">Andrew Clark</name><name sortKey="Cornish, Jacqueline" sort="Cornish, Jacqueline" uniqKey="Cornish J" first="Jacqueline" last="Cornish">Jacqueline Cornish</name><name sortKey="Dignan, Fiona L" sort="Dignan, Fiona L" uniqKey="Dignan F" first="Fiona L." last="Dignan">Fiona L. Dignan</name><name sortKey="Dignan, Fiona L" sort="Dignan, Fiona L" uniqKey="Dignan F" first="Fiona L." last="Dignan">Fiona L. Dignan</name><name sortKey="Jackson, Graham" sort="Jackson, Graham" uniqKey="Jackson G" first="Graham" last="Jackson">Graham Jackson</name><name sortKey="Mahendra, Prem" sort="Mahendra, Prem" uniqKey="Mahendra P" first="Prem" last="Mahendra">Prem Mahendra</name><name sortKey="Potter, Michael N" sort="Potter, Michael N" uniqKey="Potter M" first="Michael N." last="Potter">Michael N. Potter</name><name sortKey="Scarisbrick, Julia J" sort="Scarisbrick, Julia J" uniqKey="Scarisbrick J" first="Julia J." last="Scarisbrick">Julia J. Scarisbrick</name><name sortKey="Shaw, Bronwen E" sort="Shaw, Bronwen E" uniqKey="Shaw B" first="Bronwen E." last="Shaw">Bronwen E. Shaw</name><name sortKey="Shaw, Bronwen E" sort="Shaw, Bronwen E" uniqKey="Shaw B" first="Bronwen E." last="Shaw">Bronwen E. Shaw</name><name sortKey="Taylor, Peter C" sort="Taylor, Peter C" uniqKey="Taylor P" first="Peter C." last="Taylor">Peter C. 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